司軍強

學位：博士研究生

職稱：教授

研究領(lǐng)域：生理學-心血管生理與神經(jīng)電生理

郵箱：sijunqiang@shz.edu.cn

通訊地址：石河子大學醫(yī)學院杏一樓辦公室213號

學術(shù)兼職情況：

中國神經(jīng)科學學會理事

中國生理學會青年委員會委員

中國生理學會神經(jīng)科學專業(yè)委員會委員

中國生理學會繼續(xù)教育委員會委員

全國高等醫(yī)學教育學會綜合性大學醫(yī)學教育研究會理事

新疆維吾爾自治區(qū)生理病理生理學會生理學分會副理事長

教育部高等學校基礎(chǔ)醫(yī)學專業(yè)與課程教學指導委員會委員

新疆維吾爾自治區(qū)科學技術(shù)協(xié)會新疆自然科學專家

科研學術(shù)工作經(jīng)歷與教育背景：

1. 1989年畢業(yè)于石河子醫(yī)學院臨床醫(yī)學專業(yè)，獲得醫(yī)學學士

1995年畢業(yè)于同濟醫(yī)科大學，獲得理學碩士

2003年畢業(yè)于華中科技大學同濟醫(yī)學院，獲得醫(yī)學博士

2000年5月-2001年5月，美國俄勒岡健康和科技大學，高級訪問學者

2004年7月-2004年10月，澳大利亞國立大學，短期訪問學者

國務(wù)院政府特殊津貼專家

石河子大學學術(shù)技術(shù)帶頭人B類

獲“兵團英才”稱號。

2. 2001年獲得石河子大學碩士生導師招生資格。

2005年獲武漢大學博士研究生導師招生資格。

2007年獲得華中科技大學博士生導師招生資格。

2012年獲得石河子大學博士研究生導師招生資格。

科研項目：

新疆不同民族原發(fā)性高血壓血漿外泌體差異microRNA 篩選及臨床診斷標記物的確立——2020-2022兵團科技創(chuàng)新項目（2020AB019）

T 淋巴細胞縫隙連接蛋白通過 Notch 信號通路調(diào)控炎癥介導肺動脈高壓的研究——2022-2025兵團財政科技計劃項目（2022DZ004）

學術(shù)論文：

(1)Zan, Zhou,Wen-Jun, Jiang,Yan-Ping, Wang et al. CD36-mediated ROS/PI3K/AKT signaling pathway exacerbates cognitive impairment in APP/PS1 mice after noise exposure.[J] .Sci Total Environ, 2024, 952: 0.

(2)Tian-Feng, Shi,Zan, Zhou,Wen-Jun, Jiang et al. Hyperglycemia-induced oxidative stress exacerbates mitochondrial apoptosis damage to cochlear stria vascularis pericytes via the ROS-mediated Bcl-2/CytC/AIF pathway.[J] .Redox Rep, 2024, 29: 0.

(3)Tian-Lan, Huang,Wen-Jun, Jiang,Zan, Zhou et al. Quercetin attenuates cisplatin-induced mitochondrial apoptosis via PI3K/Akt mediated inhibition of oxidative stress in pericytes and improves the blood labyrinth barrier permeability.[J] .Chem Biol Interact, 2024, 393: 0.

(4)Zan, Zhou,Wen-Jun, Jiang,Li, Li et al. The effects of noise exposure on hippocampal cognition in C57BL/6 mice via transcriptomics.[J] .Biochem Biophys Res Commun, 2023, 690: 0.

(5)Wen-Jun, Jiang,Zan, Zhou,Yan-Ping, Wang et al. PGC-1α affects cochlear pericytes migration in noise-exposed mice.[J] .Biochem Biophys Res Commun, 2023, 687: 0.

(6)Zan, Zhou,Wen-Jun, Jiang,Li, Li et al. Noise exposure increase apoptosis in the hippocampus of AD mice through the upregulation of CTSS.[J] .Biochem Biophys Res Commun, 2023, 681: 0.

(7)Chen, Q., Kong, L., Xu, Z., Cao, N., Tang, X., Gao, R., Zhang, J., Deng, S., Tan, C., Zhang, M., Wang, Y., Zhang, L., Ma, K., Li, L., & Si, J.. The Role of TMEM16A/ERK/NK-1 Signaling in Dorsal Root Ganglia Neurons in the Development of Neuropathic Pain Induced by Spared Nerve Injury (SNI). Molecular neurobiology, 2021, 58(11), 5772–5789. (*通訊作者)(SCI收錄)

(8)Tan CY, Wang YP, Han YY, Lu BH, Ji W, Zhu LC, Wang Y, Shi WY, Shan LY, Zhang L, Ma KT, Li L, Si JQ*. Expression and effect of sodium-potassium-chloride cotransporter on dorsal root ganglion neurons in a rat model of chronic constriction injury. [J] .Neural Regen Res, 2020, 15(5):912-921. (*通訊作者)(SCI收錄)

(9)Xu ZZ, Chen QY, Deng SY, Zhang M, Tan CY, Ma KT, Li L, Si JQ*, Zhu LC. 17β-Estradiol Attenuates Neuropathic Pain Caused by Spared Nerve Injury by Upregulating CIC-3 in the Dorsal Root Ganglion of Ovariectomized Rats.[J] .Front Neurosci, 2019, 13: 1205. (*通訊作者)(SCI收錄)

(10)Zhou Y, Song J, Wang YP, Zhang AM, Tan CY, Liu YH, Zhang ZP, Wang Y, Ma KT, Li L, Si JQ*. Age associated variation in the expression and function of TMEM16A calcium activated chloride channels in the cochlear stria vascularis of guinea pigs.[J] .Mol Med Rep, 2019, 20: 1593-1604. (*通訊作者)(SCI收錄)

(11)Chang YC, Han ZW, Zhang Y, Zhou Y, Feng ZY, Chen L, Li XR, Li L, Si JQ* . G protein-coupled estrogen receptor activation improves contractile and diastolic functions in rat renal interlobular artery to protect against renal ischemia reperfusion injury. Biomedecine & Pharmacotherapie. (*通訊作者)(SCI收錄) 

(12) Qian YF, Wang Y, Tian WW, Wang S, Zhao L1, Li L, Ma KT,Jun-Qiang, Si... Effects of RMF on BKCa and Kv channels in basilar arterial smooth-muscle cells of SHR. Mol Med Rep. 2017; 16(3):2620-2626.

(13) Wang LJ, Ma KT, Shi WY, Wang YZ, Zhao L, Chen XY, Li XZ, Jiang XW, Zhang ZS, Li L,Jun-Qiang, Si. Enhanced gap junctional channel activity between vascular smooth muscle cells in cerebral artery of spontaneously hypertensive rats. Clin Exp Hypertens. 2017; 39(4):295-305.

(14) Li L, Zhang W, Shi WY, Ma KT, Zhao L, Wang Y, Zhang L, Li XZ, Zhu H, Zhang ZS, Liu WD,Jun-Qiang, Si. The Enhancement of Cx45 Expression and Function in Renal Interlobar Artery of Spontaneously Hypertensive Rats at Different Age. Kidney Blood Pressure Research, 2015, 40: 52-65.

(15) Zhang W, Ma K T, Wang Y, Li L,Jun-Qiang, Si. Inhibitory effect of 18?-glycyrrhetinic acid on KCI- and PE-induced constriction of rat renal interlobar artery in vitro[J]. Sheng li xue bao: [Acta physiologica Sinica], 2014, 66(2):195-202.

(16) Luo J, Zhang Y M, Ma K T, Li L,Jun-Qiang, Si. Difference in the expression of Kv channel in lymphocytes between spontaneously hypertensive rats and Wistar rats.[J]. 2010, 62(4):382.

(17) Guan B C ,Si JQ, Jiang Z G.Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: A whole-cell voltage- and current-clamp study[J].British Journal of Pharmacology, 2010, 151(7):1049-1060.

(18)Jun-Qiang Si, Zhang Z Q, Li C X , et al.Modulatory effect of substance P on GABA-activated currents from rat dorsal root ganglion[u]. Acta Pharmacologica Sinica,2004, 25(5):623.

(19)HuH Z, LiZ W , Si JQ. Evidence for the existence of substance P autoreceptor in the membrane of rat dorsal root ganglion neurons[J]. Neuroscience, 1997, 77(2):535-541.

(20)Jun-Qiang Si, Z W Li, H Z Hu. Inhibitory effect of baclofen on GABA-induced depolarization and GABA-activated current in primary sensory neuronsy.Neuroscience, 1998, 81(3):821-827.

(21)Jun-Qiang Si, Hui Zhao, Yugin Yang, if. Nitric oxide induces hyperpolarization by opening ATP-sensitive K+ channels in guinea pig spiral modiolar artery[J]. Hear Res, 171(1-2):0-176.

(22)Jun-Qiang Si, LiZ W, Fan Y Z. Modulatory effect of SP on GABA-and NMDA-activated currents in neurons freshly isolated from rat DRG[J]. 1996.

獲獎：兵團英才、生理學科帶頭人

承擔教學：承擔本科生《生理學》課程的教學，研究生《血管生理與病理生理學》課程的教學