宋關(guān)玲導(dǎo)師簡(jiǎn)介
發(fā)布日期:2017-11-07?? 作者:yjsbgs??瀏覽數(shù):4016

宋關(guān)玲


學(xué)位:博士研究生

職稱:教授

研究領(lǐng)域:環(huán)境污染物的毒性機(jī)制;新疆特色抗癌藥物篩選

郵箱:sglhit.student@sina.com

辦公電話:0993-2057153

通訊地址:石河子大學(xué)醫(yī)學(xué)院杏1樓辦公室733號(hào)

學(xué)術(shù)兼職情況:

華中科技大學(xué)兼職博導(dǎo)

中國(guó)毒理學(xué)會(huì)會(huì)員

新疆營(yíng)養(yǎng)學(xué)會(huì)理事

科研學(xué)術(shù)工作經(jīng)歷與教育背景:

2017-11 至今, 石河子大學(xué), 醫(yī)學(xué)院, 教授

2014-01 2017-11, 石河子大學(xué), 醫(yī)學(xué)院, 副教授

2007-01 2014-01, 山東理工大學(xué), 生命科學(xué)學(xué)院, 副教授

2002-03 2005-10,哈爾濱工業(yè)大學(xué)市政環(huán)境工程學(xué)院環(huán)境工程專業(yè),博士學(xué)位

科研項(xiàng)目:

  主持國(guó)家自然科學(xué)基金項(xiàng)目3項(xiàng),省級(jí)項(xiàng)目2項(xiàng)、校級(jí)項(xiàng)目3項(xiàng),橫向課題4項(xiàng);參與國(guó)家重大水利專項(xiàng)、國(guó)家973項(xiàng)目、中日國(guó)際合作項(xiàng)目和國(guó)家自然科學(xué)基金項(xiàng)目共6項(xiàng)。

目前主持在研項(xiàng)目如下:

  國(guó)家自然科學(xué)基金項(xiàng)目:MCUC在納米二氧化鈦致血睪屏障破壞中的作用及分子機(jī)制研究(82460651),2025年1月-2025年12月,32萬元

  兵團(tuán)重點(diǎn)領(lǐng)域科技攻關(guān)項(xiàng)目:人體多器官微流控芯片平臺(tái)的研發(fā)及在納米TiO2毒性研究和新疆特色藥物篩選中的應(yīng)用(2023AB049),2023年10月-2026年10月,220萬

學(xué)術(shù)論文:

第一或通訊作者發(fā)表研究論文50余篇,其中30余篇被SCI\EI收錄,主編學(xué)數(shù)專著3部。近5年通訊作者發(fā)表17篇SCI收錄研究論文如下:

1.The role of CXCL13 in GC-1 cell cycle arrest induced by titanium dioxide nanoparticles through JAK2/STAT3 signaling pathway. Appl Toxicol. 2024on line.(通訊作者)

2.Study on the mechanisms of defective spermatogenesis induced by TiO2 NPs based on 3D blood? testis barrier microffuidic chip[J].Toxicology,2024,507:153888 10.1016/j.tox.2024.153888.(通訊作者)

3.Titanium Dioxide Nanoparticles Induce Cell Cycle Arrest andApoptosis through Inhibiting PI3K/AKT/mTOR Pathway in Spermatogonia[J].Biological Trace Element Research, 2024, 202(9).DOI:10.1007/s12011-023-03984-7.(通訊作者)

4.Titanium dioxide nanoparticles induce apoptosis through ROSCa2+-p38/AKT/mTOR pathway in TM4 cells[J]Appl Toxicol. 2024;1–15.DOI: 10.1002/jat.4583.(通訊作者)

5.The status and influencing factors of lung ventilation function in employees exposed to dust in enterprises of the XPCC, China [J].Frontier in Public Heaith,2024,1-18.DOI10.3389/fpubh.2024.1370765.(通訊作者)

6.The ROS Mediates MCUb in Mitochondria?Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles [J].Biological Trace Element Research, 2024,DOI:org/10.1007/s12011-024-04339-6.(通訊作者)

7.The Role of PI3K/AKT/HIF- 1α.Pathway in the Effect of Nano- TiO2 on Lactate Production in TM4 Cells.Journal of Applied Toxicology, 2024; 0:111.(通訊作者)

8.Protective Effects of lycopene on TiO2 Nanoparticle-induced Damage in The Liver of Mice[J]. Journal of Applied Toxicology, 2023436)913-928. doi: 10.1002/jat.4433.(通訊作者)

9.Nanosized Titanium Dioxide Induced Apoptosis and Abnormal Expression of Blood-Testis Barrier Junction Proteins Through JNK Signaling Pathway in TM4 Cells[J]. Biological Trace Element Research, 2022, 200(12):5172-5187. doi: 10.1007/s12011-022-03099-5.(通訊作者)

10.Effect of Titanium Dioxide Nanoparticles on Mammalian Cell Cycle In Vitro: A Systematic Review and Meta-Analysis[J]. Chemical Research in Toxicology, 2022, 35(9):1435-1456. doi: 10.1021/acs.chemrestox.1c00402.(通訊作者)

11.Effects of Nano-titanium Dioxide on Calcium Homeostasis in Vivo and in Vitro: A Systematic Review and Meta-analysis [J].Toxicology Mechanisms and Methods, 2022 , 19:1-11. doi:10.1080/15376516.2022.2124137.(通訊作者)

12.Nano-titanium Dioxide Exposure and Autophagy: A Systematic Review and meta-analysis[J].Toxin Reviews, 2022,6:1-12.doi: 10.1080/15569543.2022.2084419.(通訊作者)

13.Genotoxicity Evaluation of Silica Nanoparticles in Murine: A Systematic Review and Meta-analysis[J]. Toxicology Mechanisms and Methods, 2022, 32(1): 1-17. doi: 10.1080/15376516.2021.1965277.(通訊作者)

14.Lycopene Alleviates Titanium Dioxide Nanoparticle-induced Testicular Toxicity by Inhibiting Oxidative Stress and Apoptosis in Mice[J]. Biological Trace Element Research, 2021(on line). doi: 10.1007/s12011-021-02881-1.(通訊作者)

15.Effect of Nano-titanium Dioxide on Blood-Testis Barrier and MAPK Signaling Pathway in Male Mice[J].Biological Trace Element Research, 2021,199:2961-2971. doi:10.1007/s12011-020-02404-4.(通訊作者)

16.Genotoxicity Evaluation of Titanium Dioxide Nanoparticles in Vitro: a Systematic Review of the Literature and Meta-analysis[J]. Biological Trace Element Research,2021, 199: 2057-2076. doi: 10.1007/s12011-020-02311-8

17.Oxidative Damage Induced by Nano-titanium Dioxide in Rats and Mice: a Systematic Review and Meta-analysis[J]. Biological Trace Element Research, 2020, 194(1):184-202. doi: 10.1007/s12011-019-01761-z

承擔(dān)教學(xué):承擔(dān)本科生《環(huán)境衛(wèi)生課程》的教學(xué),研究生《環(huán)境與健康》課程的教學(xué)

導(dǎo)師寄語:

年輕人,你的職責(zé)是平整土地,而非焦慮時(shí)光。你做三四月的事,在八九月自有答案。


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